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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dac7c1b9d16b4466b4423b5796de1e13a27c78868e08b9de85dfc136d7612b4' 
  AND token = 'tLilDGZAQDetaUEqndZn2Jk8GXDKwKhY5i9zNuA9FFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}