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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308c522b0685396aa88988249889419f6d1b18e8604a3a8e93de17f4f689db24' 
  AND token = 'qJqmpGfRFZPWM+b9kgOeVTw4UANN0rT4GPcLWQ2cYW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}