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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cce25c1b379f5eb447931a4d0b374de7e88ea40424c3fa6773e1d3bbaf7c2060' 
  AND token = '+F+NuIgrYES08uc8Jvku0WeBvBuVd64LuobrmJEcAyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}