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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cff3101bb3be9124ed2f0b234c3845da2cb609d554034d864cbe525b728f481f' 
  AND token = 'a8dU+Klob64fAMW38WW0167dWzPFCdqvhvj+D4lM0Ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}