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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5a37af20208d290c9075f2e5e65f8e2a656cc73100e5d6444747b53f8ab6f5' 
  AND token = '2hHS17hUz9CNnxEboQai8JJwN8cfaLeMgcdsaCquSek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}