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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6821632c2458ed9d121244f3e0b91abf0e4bfa0701096e13dd97e2c52db20c' 
  AND token = 'KPPPYY1HPaOcRoWS5qAjzzvwDxauMGPmpdk98tiFuGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00158

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}