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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dafe4396864d8cd3651e7d7493cc01d5d444989d4eda33a75701e90fcf9084a' 
  AND token = 'uFtJJAeghx1gmYs5x4q67w20A9jNqIbJfnvJB5BE1Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}