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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622fe91bb568682af6d3bfd14facdea10ab8acc8273b1f60fa1aec7dea244c06' 
  AND token = 'XTLmi9UDTbwbHql65g2DUBgJ5xVZGCSrid2f5biC/dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}