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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d27a7466e6f5077268075038b9997d449e65b976283d1e18550d1a4f7d9f865' 
  AND token = 'Gc0n7pU+PglLWqjS515QLEExPfnIhTRRScFMynyLVyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}