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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88c487ffc8c6544351ad28d05295e8833f3c89af5c85ac6ba8435fbeb6645e80' 
  AND token = '1/aZ+Y2DyCwW5xPVOvmGu5cuxJtyYUqlRzVu096CF8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}