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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1e6b78d965b7e604f5bd01045a9e073b567d832817e9871500a50dda96c4e8' 
  AND token = 'w0cs6QTgIoeBb2vgR586rfA7ajRRLk+fMeTbv6lbngM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}