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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c19f5b0ce71a59d8dd86e040830b73968819ca222458278feebd765f8e59d0c3' 
  AND token = 'E1XX0bBt0doY8zkV41VQKOrGGRsXDh2ZgatFjwQAq48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}