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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '007753fd8ff6c72307213c20737acd466ea8f8b350e8787e83320b16071ab72f' 
  AND token = 'WF9+SOmgEH/LC3wUUVH0tuLLhkrfgZzA+yJ0rvUzpCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}