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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8d8b73af366b0119e00c40c937f79dcf5a7fe4cba8a06e916b13e286f85ae8' 
  AND token = 'Wt2xVYMKbP8y3yYbl7fB9zCbDsc8/nV/tjhEqrjKS78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}