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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61291b4a410d5e43cae57bc646b5ba937282f543f79035d77c17ae54f900c902' 
  AND token = 'PV1vMsdeUYB/pgu3TjEZ3rD2FUFAFR6kUdNH5eExq8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}