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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c456a7a56abb016a115b18de7100ef584dd4c72db6f0e5ecd1d2d1850233d0' 
  AND token = 'aHQlCJLxDnVr4fixWZ41fGZ0lWqkSlQsR3qXgZg7+TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}