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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456e4ae7f45d34aa074f2f8172e112975fd5e208f551fbd6ed345cd35686ce93' 
  AND token = 'DXbV4Efu+R9+LWDWij0hZuNWZlHH++YzKt3727ptBkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}