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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5022de6017b1f49aa853b2c58b4541552a7925629943b8765f2d2d7decec04' 
  AND token = 'IVJv0tu4bDjAu8PD+XRYIsn/m2lUUntTYKAy1Yi5r3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}