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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5b993f495516e9dcec65ad225489b2400da0e72242d17583f691d8a2fe58c7' 
  AND token = 'ip4BYZUG94E2Qfh+bfP8I7rxAO1iYKqph3v6j3zke4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}