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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4b08e1d8c3c2302c5e33bfcdb74b2bdf48964ae497812969296f5572632cb4f' 
  AND token = 'rR6DFxfQCvXwlpF/6wu8wmsfKEt3WXr8kVthzlI5/Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}