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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf4ef89b8e481782c4d520e7c763a05d6ddb5273aa9adf1e15cc4318989a546' 
  AND token = '83+MuQfAK+sCw+PHb9TgLe4511XB8+vsShgNMzQdorQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}