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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ea9f7f2f75725bd85fd18806a49b15e2a49e4db48f3dc8d0e09755d55c5c6a' 
  AND token = 'oCZUciU22mtobMF3t5/xzP5VAcGVNpy/j9e//1y5OKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}