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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e05facdeac1940e50cb702d225f147d8000244e5cbb2f03d433ce3321bb459b' 
  AND token = '/5J0Qxq0IbyUR1MuayPgItjL8++XyQL7hiyZzCFtivA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}