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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8309f7ed844a83e698606f5e25cba521b7a5b32a6bf77304a6f16d6f32d2f0a1' 
  AND token = 'D0udhNvocYcVKfJ8lxhTS0Ft+1Ysx2y6o3ZNf2vEkuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}