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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649b8ffbf037b7571e490e83af2c8b41bb2dcaf89f13e9fbeb88c21353788f1f' 
  AND token = 'hxrBocwHDOjaC2OC8v51au2qn7xJ6r+xwG5cmSS0tWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}