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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45752f1df38d72f9d2b07760c3c6b3b990e53123e8ab431b29d0e8ed44e375b' 
  AND token = 'lFclyfvaOl9ng0/is9Vj/ybt21b7g86EiIDjXN7/RnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}