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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384df8b8e74dc0f040bcf6ddb0255a12c058896a2e6e1d6fd36c31852e81abe3' 
  AND token = 'XNqr/bxIXQh4rEcrVG9aVC0rPg/jUVw3LMQ73/BTsUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}