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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cab44514847eda442776200db395a861d587f7d04025e5f1f0580e6f2646915' 
  AND token = '+eAQ2ZEMc4lnQKB7oirTDqnVOrAM+My9ZwxEJR4Bks0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}