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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b5a399f6c099d2e5881220f5f09ebc07660645bed4618241a33c1eaa5d683b' 
  AND token = '9iLQKJYBp0rXm0gvFxZsemn8D5SbeTNnRTgSxeykkP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}