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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bdf003a7dde701ee86bd8fcfda19189454bc4cde61a67e0eaa7c74812e963b0' 
  AND token = '43AhB+wMa5PCusFpl7pFpvsoRuGN7JNV8ZtKpRXnDyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}