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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '610e5a9f8cd8164f9d9e0dced4c9823ec982e4725637dc7cc1764ed42dedc0b6' 
  AND token = 'ySwlKkSWN6Qtsr6YuWTqkkB6hE0pPbgiSg4MFUN4EgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}