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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52c2441f016731f750b3dfe5526843cfca56ed870a181a03983c2012f432618' 
  AND token = 'XggFD0tFKd9A0k27ES/w1pmwReRJ9CRsUweiwfEmS7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}