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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef5970f2b2f5923ec0215b554492feacc4714648bab59787816891f28877fd09' 
  AND token = 'w/0Sg3CKHcUfOgPumc5igld2VoKH7pTpQgwHDju6y6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}