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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72746d8fd63eb01795aa8122d7b83b7bd3a2428743a0c1060428597d60fc4cc5' 
  AND token = 'XP8oou9JG76T9+++HYBeL9lAuK+tJBxa87rRf6IPmvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}