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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e362ef1fdd2719dd35e76e7d8bc29b1c315ee3c224acb6998a1954203eaf770b' 
  AND token = '/KLuVbYG4V46xoN0j1SsOhl8TpMwJ3KT8n4WTjSDYmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}