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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24946472129c9b902cb747f1ded5b0551b5dbc324cd4bbaba3e5f4793cfcf33b' 
  AND token = 'qvzcuiNCpZBG/f7CAefYQYeV35bZ3b/3GY9AXEC+Q/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}