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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95b737b95f55b18751621c6a044694ee59535d12af0c3c6d6f549a9eb052c095' 
  AND token = 'ApNIS/Mk0DK+zXWAS5U7X6lk9w7sDIbfoW/XZKaBwyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}