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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca7fb6136646a61d1cecfa4a761c1755e34772c16e1774d9054ec7fee1b533b' 
  AND token = '4PvDdYb5+CSoczEb6BPLZGT2jmKbrkE8gF6Z+dtszac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00105

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}