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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e49d50ff4f4fef109efa10c465afd91fca9334fcd37b195688b3b2d1d76bf10' 
  AND token = '5rVmyqEHybcxDJeO1AhkFQHLAL8Z6klYwbm9jCe/y8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}