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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab2221020af10493dc0be35e8614b3ba94a058e4daa20c0220c64049c174ef09' 
  AND token = 'kLbSwyrsBWan+sF0/k2txFixPD9ljKl6vKAC/fIghPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}