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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3acc12fa49a7676e62636e5345b727ebb111f09d5f646d37fc6b789d13aab406' 
  AND token = '8UZUfP04hF40PuPTNLImtQncEv4gD/XyqQ8tA4pWeVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00172

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}